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The Critical Mistake: What is Lean Mass? Now, heres one shocking fact: no study had yet directly explored how incretin-based poly-agonists, tirzepatide (GLP-1-GIP) and retatrutide (GLP-1-GIP-Glucagon) affect skeletal muscle
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Lenny Macrina: Right, and they talk about swelling, joint pain, anxiety, panic attacks, heart palpitations, insomnia, drowsiness, weakness, fatigue, loss of appetite, depression, anhedonia
Saito, C
Among available substrates, fatty acid -oxidation represents the principal energy source, accounting for approximately 70%90% of ATP generation, whereas glucose oxidation, lactate utilization, and ketone body oxidation serve as complementary contributors to cardiac energy metabolism (55)
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